• Description

  • Application Data


DBCO-PEG4-Amine is a carboxyl-reactive building block with a PEG4 spacer arm.

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Application Data

Catalogue number crb7108354
Molecular Weight 523.62
Chemical Composition C29H37N3O6
Appearance Yellow to slightly orange oil
Solubility DMSO, DMF, DCM, THF, Chloroform
Chemistry Amine
Purity >95% (HPLC)
cas 1255942-08-5
Storage -20C
Manufacturer Product Number A103P
Material Safety Data Sheet (MSDS)

DBCO-PEG4-Amine is a carboxyl-reactive building block with enhanced solubility in aqueous media used to derivatise carboxyl groups in the presence of activators (e.g. EDC, DCC) or activated esters (e.g. NHS esters) through a stable amide bond. DBCO reagents (ADIBO/DIBAC) are the most commonly used substrates for copper-free Click chemistry. DBCO compounds react with azide-containing compounds/biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The hydrophilic PEG linker increases the solubility of the compound in water.


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