Antibodies

TARGET Antibodies

target-antibodiesThis service provides the highest quality of target specific custom polyclonal antibodies that we offer. There are many steps to generating a custom antibody and care and attention to every detail and many years of refining the process at every stage have given CRB its enviable track record. We bring both a chemical and biological perspective to antigen design, while our first-rate project management and purification strategies help guarantee a high success rate for the production of polyclonal antibodies.

We offer an a la carte menu for greater success and flexibility which typically follows the stages: Antigenic predictionpeptide synthesiscarrier conjugationimmunisationELISA screeningAffinity Purification.

In addition, we offer validation by western blot analysis, modification (Fab fragmentation) and labelling (fluorescent, biotin or enzyme) of antibodies.

Major benefits of ordering this service are:

  • Free Consultation
  • Expert advice on the vital first step of antigen selection
  • From either your target protein or peptide sequence

Pure™ Peptides

  • Cleaner product: Peptide antigens are synthesised in-house and purified by HPLC
  • Peace of mind: Peptides are conjugated in-house and monitored for combination
  • High specificity and yield of purified antibody due to the quality of the peptide affinity media prepared in-house

Superior Quality

  • We use only high quality animals housed in UK Home Office, USDA & NIH compliant facilities
  • A variety of species and screening strategies employed for best approach
  • ISO9001:2015 Quality Accreditation

Project Management

  • Close involvement between CRB and client’s own goals to steer project
  • Fully-managed data from antibody generation programme
  • Data available in ‘real time’ via my account, or in format specified by researcher

A Record of Success

At CRB we pride ourselves on the quality of our antibodies. According to customer feedback:

  • 100% of antibodies raised against peptide recognise the peptide antigen
  • 70% of these antibodies react with protein by Western Blot
  • 50% of these antibodies react with protein in immunohistochemistry