Biotin SBP1
Biotin-[PEG4]-IEEQAKTFLDKFNHEAEDLFYQS-amide
Description
Application Data
Description
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Fragment of the ACE2 peptidase domain (PD) α1 helix, a domain important for the interaction of ACE2 with the SARS coronavirus receptor binding domain (SARS-CoV-2-RBD). Peptide contains a covalently bonded N-terminal Biotin tag and a polyethylene glycol spacer (PEG4).
Application Data
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Data Sheet Material Safety Data Sheet (MSDS)Catalogue number crb1001497 Sequence (one letter code) Biotin-[PEG4]-IEEQAKTFLDKFNHEAEDLFYQS-amide
Sequence (three letter code) Biotin-[PEG4]-Ile-Glu-Glu-Gln-Ala-Lys-Thr-Phe-Leu-Asp-Lys-Phe-Asn-His-Glu-Ala-Glu-Asp-Leu-Phe-
Tyr-Gln-Ser-NH2Modifications where PEG4 is polyethylene glycol and acts as a hydrophillic spacer Purity >95% Storage -20°C References Zhang et al (2020). The first-in-class peptide binder to the SARS-CoV-2 spike protein. bioRxiv preprint March 20. https://www.biorxiv.org/content/10.1101/2020.03.19.999318v1
Manufactured in: United Kingdom Fragment of the angiotensin-converting enzyme 2 (ACE2) peptidase domain (PD) α1 helix, a domain important for the interaction of ACE2 with the severe acute respiratory syndrome (SARS coronavirus receptor binding domain (SARS-CoV-2-RBD). SBP1 associates with the SARS-CoV-2-RBD with nanomolar affinity and can potentially block the key mechanism by which SARS CoV-2 initiates entry into human cells.
This peptide has a covalently bonded N-terminal Biotin tag that can be used for detection and purification and contains a polyethylene glycol spacer (PEG4).
Biotin SBP1
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