An antibody target is the molecular part of the cell an antibody recognises. This could be on the cell surface, such as a receptor on an antigen overexpressed on tumour cells. Each antibody recognises a specific epitope; an interaction can then modulate an outcome.
An antibody’s target is ideally easily accessible with a characterised expression, such as an increase in pathological tissue. These conditions are complemented by the target being found at detectable concentrations, which aids the quantification of antibody binding. For example, therapeutic antibody treatments can rely on blocking the interaction of a ligand with a receptor by using an anti-ligand antibody or an anti-receptor antibody. Cambridge Research Biochemicals provides antibodies to a wide range of targets, including coronaviruses and succination, to further these areas of research.