DBCO Maleimide is a sulfhydryl-reactive labelling reagent
Catalogue number crb7108359 Molecular Weight 427.75 Appearance Slightly grey crystalline Solubility DMSO, DMF, DCM, THF, Chloroform Chemistry Maleimide Purity >95% (HPLC) cas 1395786-30-7 Storage -20C
DBCO Maleimide allows for simple combination of a DBCO group and cysteine-containing peptides and other thiol-containing molecules. The maleimide group reacts with sulfhydryl groups at pH 6.5 – 7.5 to form stable thioether bonds. Its long length enhances accessibility of the azide-reactive DBCO and of reactive thiols, which may be buried.