DBCO Maleimide

  • Description

  • Application Data


DBCO Maleimide is a sulfhydryl-reactive labelling reagent

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Application Data

Catalogue number crb7108359
Molecular Weight 427.75
Appearance Slightly grey crystalline
Solubility DMSO, DMF, DCM, THF, Chloroform
Chemistry Maleimide
Purity >95% (HPLC)
cas 1395786-30-7
Storage -20C
Manufacturer Product Number A108
Material Safety Data Sheet (MSDS)

DBCO Maleimide allows for simple combination of a DBCO group and cysteine-containing peptides and other thiol-containing molecules. The maleimide group reacts with sulfhydryl groups at pH 6.5 – 7.5 to form stable thioether bonds. Its long length enhances accessibility of the azide-reactive DBCO and of reactive thiols, which may be buried.

DBCO Maleimide

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