Technical information for peptide and antibody products


CRB synthesises and supplies a wide range of modified peptides. Some examples are listed below:


  • Acetyl, benzoyl, formyl
  • Biotin
  • Dyes – Alexa, Cy, AttoTec, Chromis, FAM, TAMRA, Dabcyl, Dabsyl, Dansyl
  • DOTA & DTPA (metal chelators)


  • Amide or acid
  • AMC (for fluorogenic substrates)
  • Esters (methyl, ethyl etc)
  • Hydrazide
  • Peptide aldehydes (for protease inhibitors and chemical ligation)
  • Peptide hydroxamic acids (for protease inhibitors)
  • Substituted amides (methylamides, dimethylamides etc)
  • Thiol esters (for chemical ligation)

Unusual amino acids

  • D-amino acids
  • α-N-methyl amino acids
  • ε-N-methylated lysines, NG-methylated arginines
  • Phosphoserine, phosphothreonine, phosphorotyrosine
  • Sulfotyrosine
  • Hydroxyproline
  • Amino acid analogues and homologues
  • Peptidomimetics

Other modifications

  • Intermolecular disulphide bridges
  • Lipids (farnesyl, stearoyl etc)
  • N-C cyclisation
  • PEGylation
  • Side-Chain Linked (β-Asp, γ-Glu, ε-Lys)

This is not an exhaustive list and we will be pleased to discuss the synthesis of any modified peptide you require.