Anti-SLC15A4 antibody
Description
Application Data
Description
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Recognises SLC15A4 with high affinity. SLC15A4 is a membrane bound histidine/oligopeptide transporter involved in autoimmunity
Application Data
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| Catalogue number | crb2005113 |
|---|---|
| Antibody | Anti-SLC15A4 antibody |
| Antigen Peptide | KLH conjugated synthetic peptide crb1200375 |
| Protein ID | UniProtKB - Q8N697 |
| Aliases | Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1 |
| Cross-Reactivity | Human |
| Host Species | Anti-Rabbit |
| Antibody Type | Polyclonal |
| Concentration | 0.2mg/ml |
| Target | SLC15A4 |
| Storage | This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles. |
| References | Griffith, A., Zaidi, A., Pietro, A., Hadiono, M., Yang, J., Davis, R. and Popkin, D. (2018). A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice. Sci Rep, 8(1). PMID: 30262916
Kobayashi, T., Tsutsui, H., Shimabukuro-Demoto, S., Yoshida-Sugitani, R., Karyu, H., Furuyama-Tanaka, K., Ohshima, D., Kato, N., Okamura, T. and Toyama-Sorimachi, N. (2017). Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells. Int Immunol, 29(12), 551-566. PMID: 29155995
Yamashita, T., Shimada, S., Guo, W., Sato, K., Kohmura, E., Hayakawa, T., Takagi, T. and Tohyama, M. (1997). Cloning and Functional Expression of a Brain Peptide/Histidine Transporter. J Biol Chem, 272(15), 10205-10211. PMID: 9092568 |