Anti-KSHV ORF65 antibody

  • Description

  • Application Data

Description

 

An antibody raised against guanylate cyclase soluble subunit alpha-2 (GUCYA2); GUCYA2 is a negative regulator of guanylyl cyclase activity.

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Application Data

Catalogue number crb2005224
Antibody Anti-KSHV ORF65 antibody
Antigen Peptide KLH conjugated synthetic peptide crb1200467e
Protein ID GenBank: ABD28922.1. UniProtKB - Q2HR63
Aliases Kaposi sarcoma-associated herpesvirus (KSHV) ORF65, Human gammaherpesvirus 8 ORF65, HHV-8 ORF65, Small capsomere-interacting protein
Cross-Reactivity KSHV
Target Protein Species KSHV
Host Species Rabbit
Antibody Type Polyclonal
Concentration 0.5 mg/ml
Validation WB (1:100), ELISA (1:1000)
Target KSHV ORF65
Storage Stabilisers The product should be stored at -20°C for for short term storage and long term storage. Avoid repeated freeze/thaw cycles.
Specificity Protein
Storage The product should be stored at -20°C for for short term storage and long term storage. Avoid repeated freeze/thaw cycles.
References

Lin et al., (1997). Identification, expression, and immunogenicity of Kaposi’s sarcoma-associated herpesvirus-encoded small viral capsid antigen. J Virol., 71(4): 3069. PMID: 9060668.

Chen et al., (2020). Human immunodeficiency virus-associated exosomes promote Kaposi’s sarcoma-associated herpesvirus infection via the epidermal growth factor receptor. J Virol.94(9): e01782-19. doi: 10.1128/JVI.01782-19.

Material Safety Data Sheet (MSDS)

Antibody which recognises lytic-phase viral capsid antigen (vp19)/small viral capsid antigen (sVCA), encoded by open reading frame 65 (ORF65) from Kaposi’s sarcoma-associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8). HHV8/KSHV belongs to the gamma-2 or rhadinovirus sub-lineage of the Gammaherpesvirinae subfamily and is strongly associated with AIDS related malignancies. These malignancies include; Kaposi’s sarcoma (KS) – a rare cancer that causes skin and mouth lesions; primary effusion lymphoma (PEL) – a B-cell lymphoma; and Castleman’s disease – characterised by over proliferation of the lymph node.

Anti-KSHV ORF65 antibody

Cat No.Pack SizePriceQty.
20µg£130.00
20µg£250.00
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