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CRB Discovery

Spectrum Peptides: Full Spectra

Cambridge Research Biochemicals offers the full emission spectra of fluorescent labelled peptides

Chromis dyes: New fluorescent labels

The CHROMIS product line is a selection of the newest fluorescent labels available today.

Dye Selector: Choosing the best Dye

Our dye selector will take you through a step by step process to help you choose the best dye.

Spectrum Peptides
Cambridge Research Biochemicals offers the full emission spectra of fluorescent labelled peptides: Spectrum Peptides
Find out more
Light Up Peptides
Fluorescent Peptides Help Nerves Glow in Surgery

In a recent Nature Biotechnology paper, authors have found potential for fluorescent peptides to illuminate nerves during surgery. A frightening complication of surgery can result in paralysis, chronic pain from unintended peripheral nerve damage. To visualise and avoid these nerves has always been challenging. For example, if the nerves are invaded by a tumour, or, if surgery is required in the setting of trauma or infection, the affected nerves might not look as they normally would, or their location may be distorted. Scientists at the University of California San Diego (UCSD) have developed fluorescent peptides; referring to these as “Light-up Peptides” to visualise nerves during surgeries.

Read more Take a look at our fluorescent labels
Spectrum Peptides


CRB has the most comprehensive range available of
licenced and free-to-use activated fluorescent dyes for labelling peptides.


CRB brings thirty years of experience of labelling peptides with fluorescent dyes and will advise on the synthesis strategy for most efficient use of dye and hence cost-effectiveness.


CRB provides a dye selector tool and a technical support service to best match dye choice with intended application and excitation source.

Licenced Proprietary dye range:


Cy™ dyes from GE-Amersham Biosciences


Alexa Fluor® dyes from with Life Technologies-Molecular Probes


ATTO dyes from Atto-Tec


Black Hole Quenchers from Biosearch Technologies


CRB can now offer a custom dye design and synthesis option for development of dyes for specific projects which need to vary structure, reactivity or charge of dyes including new derivatives.


Leave it to the experts, contact CRB Discovery for all your fluorescent labelling needs be it peptide, protein, antibody or small molecule.

More about fluorescent peptides
CHROMIS Dyes Take a look at our Spectrum Peptide section on our website to find out more

Cyanagen are CRB’s latest supplier of bright, cost-effective and non-proprietary (free to use) fluorescent dyes. The CHROMIS product line is a selection of the newest fluorescent labels available today. Dye structures were carefully chosen to provide top-notch brightness performances, improving bioanalytical assays to the highest level.

Eight different basic structures span the full working range of wavelength, starting from 400 nm up to 870 nm. Each fluorescent compound is available with many different reactive moieties while retaining the photophysical features of the parent dye.

Furthermore, a completely new level of chemistry has been developed to provide the same fluorescent label with different charge values (anionic, cationic, zwitterionic and neutral).


Olivier A. Pierrat, Kvido Strisovsky, Yonka Christova, Jonathan Large, Keith Ansell, Nathalie Bouloc, Ela Smiljanic, Matthew Freeman

Monocyclic β-Lactams Are Selective, Mechanism-Based Inhibitors of Rhomboid Intramembrane Proteases

ACS Chemical Biology In Publication


Webb S.E.D, Roberts S.K, Needham S.R, Tynan C.J, Rolfe D.J, Winn M.D.
Clarke D.T, Barraclough R, Martin-Fernandez M.L

Single-Molecule Imaging and Fluorescence Lifetime Imaging Microscopy Show Different Structures for High- and Low-Affinity Epidermal Growth Factor Receptors in A431 Cells

Biophysical Journal, 2008. 94(3), 803-819


Need to know more?
Contact us by visiting our website
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for more information
Dye Selector

Our dye selector will take you through a step by step process to help you choose the best dye for your application.

Click here
Dye Selector Wheel

With licenses to supply materials labelled with GE Healthcare’s Cy™ Dyes and Life Technologies - Molecular Probes’ Alexa Fluor® dyes range, we offer the most comprehensive custom labelling service for fluorescent peptides.

A range of red, green and blue dyes are available to support a wide variety of discovery technologies such as FRET or multiplex assays and fluorescence microscopy. Our innovative online dye selector provides a list of suitable dyes matching your wavelength and provides the necessary technical data to enable choice of dye fit for purpose. Alternatively you can talk to us directly for advice on your specific application.

Request a Quotation

Should you require a quotation from any of our custom services, we have a clear cut and easy system that enables you to do so. Follow these three simple steps:

Request a Quotation - Step 1 Request a Quotation - Step 2 Request a Quotation - Step 3

Go to:

Simply click on the relevant tab and register your details.

Once issued with a password you can then log on to our quotation system using your customer account log-in and a quotation will be issued within 24 hours.

At Cambridge Research Biochemicals we have a fast-track quotation system that tailors your requirements, gives you all the information you need and a specific price within 24 hours. You are also given a personal contact so that if you have any further questions you can directly contact one of our approachable representatives who has the technical knowledge to assist you.

Meet a CRB representitive

If you would like any support, help or technical advice we would like to hear from you.

CRB is delighted to be sponsoring the Cambridge Cell Biology Seminar Series and the next event is being held on 7th March 2011
Professor Paul Martin-University of Bristol: Parallels between wound healing and cancer
Adhesive control of cell polarity, organelle positioning and cell division axis in growing cells and of primary ciliogenesis in cell-cycle arrested cells
7th March 4pm Sackler Lecture Theatre Lent Term University of Cambridge
Click here to find out more
CRB will be exhibiting and attending the following exhibitions:
Wound Healing and Cancer Seminar Bench to Boardroom
Peptide Arrays Meeting AACR

T+44 (0)1642 567180
F +44 (0)1642 567181

17-18 Belasis Court, Belasis Hall Technology Park, Billingham, Cleveland, TS23 4AZ United Kingdom