Histone mutations play important roles in DNA organisation

Posted by & filed under Antibodies, Blog, Discovery Antibodies, Post-Translational Modifications, TARGET Antibodies: Polyclonal Antibody Production.

Discovery antibodies a select set of catalogue antibodies

Histone proteins help compact and organise the DNA of the nucleus, they also play key roles in orchestrating gene expression. The four core histones, H2A, H2B, H3 and H4 form a complex around which DNA is wound forming the nucleosome. Between the nucleosome is the internucleosomal DNA which is stabilised by the linker histone H1. Modifications of histones can alter the nature… Read more »