Alexa Fluor® 488 Anti-β-actin antibody
Description
Application Data
Description
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Detects β-actin proteins. Used as an internal control for experiments. Conjugated to Alexa Fluor® 488 fluorescent dye
Application Data
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Data Sheet Material Safety Data Sheet (MSDS)Catalogue number crb2115000e Antibody Alexa Fluor® 488 Anti-β-actin antibody Antigen Peptide KLH conjugated synthetic peptide crb1200274e Protein ID UniProtKB - P60709 Aliases ACTB, BRWS1, PS1TP5BP1, Beta-actin, β actin, β-actin, βactin Cross-Reactivity Human, Rat, Mouse Host Species Anti-Rabbit Antibody Type Polyclonal Label Labelled with Alexa Fluor® 488 under optimal conditions. Ex: 495nm Em:519nm Concentration 0.57mg/ml Validation ELISA Target β-actin Disease Area Cell motility, structure and integrity Family Internal cellular protein Specificity Protein Post-translational Modification None Citations Dugina, V., Khromova, N., Rybko, V., Blizniukov, O., Shagieva, G., Chaponnier, C., Kopnin, B. and Kopnin, P. (2015). Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget, 6(16). PMID: 26008973
References Dugina, V., Khromova, N., Rybko, V., Blizniukov, O., Shagieva, G., Chaponnier, C., Kopnin, B. and Kopnin, P. (2015). Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget, 6(16). PMID: 26008973
Antibody that detects β-actin proteins. Actin is a highly conserved structural protein that forms microfilaments, one of the main structural components of the cell cytoskeleton. Actin is therefore found at high concentrations in all cell types. Actin may also function as a tumour suppresser. β-actin is one of the three main actin isotypes and is a non-muscle cytoskeletal actin. β-actin is relatively stable and appears to remain at constant levels regardless of experimental treatment, it is generally used as an internal control for experiments.
This antibody is conjugated to Alexa Fluor® 488. Alexa Fluor® 488 is a popular bright green fluorescent dye with high pH-stability.