Tetanus Toxin (1174-1189)
Tetanus Toxin (1174-1189) is a protein that is derived from the single-chain polypeptide neurotoxin produced by Clostridium tetani.
Catalogue number crb1001482 Molecular Weight 1984 Sequence (one letter code)
Sequence (three letter code)
Purity >95% Storage -20°C References
Pellizzari et al (1999). Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses. Philos Trans R Soc Lond B Biol Sci. PMID: 10212474
Surana et al (2018). The travel diaries of tetanus and botulinum neurotoxins. Toxicon. PMID: 29031941
Manufactured in: United Kingdom
Tetanus Toxin (1174-1189) is a protein that is derived from the single-chain polypeptide neurotoxin produced by Clostridium tetani. The neurotoxins produced by Clostridium tetani are among the most potent molecules known to humankind. Once in the body, the toxin binds to the basal lamina at the neuromuscular junction. From here, the toxin is transported to inhibitory interneurons in the spinal cord, where it prevents the release of neurotransmitters, which causes spastic paralysis.