Temporin A FLPLIGRVLSGIL-amide

  • Description

  • Application Data

Description

Short, linear anti-microbial peptide most potent against Gram-positive bacteria, including biofilms 

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Application Data

Catalogue number crb1000023
Molecular Weight 1396.76
Sequence (one letter code) FLPLIGRVLSGIL-amide
Sequence (three letter code) H-Phe-Leu-Pro-Leu-Ile-Gly-Arg-Val-Leu-Ser-Gly-Ile-Leu-NH2
Molecular Weight 1396.76
Purity >95%
Storage - 20 ° C
References

Capparelli et al (2009) Synergistic Antibacterial and Anti-Inflammatory Activity of Temporin A and Modified Temporin B In Vivo. PLoS ONE 4(9) e7191 PMID: 19784377

Di Grazia et al (2014) Temporins A and B Stimulate Migration of HaCaT Keratinocytes and Kill Intracellular Staphylococcus aureus. Antimicrob. Agents Chemother. 58(5) 2520 PMID: 24514087

Data Sheet Material Safety Data Sheet (MSDS)

Temporin A is a short, linear, basic and highly hydrophobic anti-microbial peptide (AMP) isolated from the frog, Rana temporaria. Temporin A is particularly active against Gram-positive bacteria including those arranged in biofilms. Temporin A is also active against some Gram-negative bacteria and Leishmania parasites.

Temporin A adopts an α-helical conformation in a membrane-mimicking environment and is able to perturb the membrane of microbial cells. Temporin A is practically non-haemolytic up to concentrations five-times higher than their minimum inhibitory concentration (MIC) against Gram-positive bacteria

Temporin A

Cat No.Pack SizePriceQty.
1mg£110.00
0.5mg£85.00
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