SARS-CoV-2 Spike (816-825) SFIEDLLFNK-acid

  • Description

  • Application Data

Description

SARS-CoV-2 Spike (816-825) is a tryptic peptide marker identified as an antigen.

See full description

Application Data

Catalogue number crb1001579
Molecular Weight 1224.6
Sequence (one letter code) SFIEDLLFNK-acid
Sequence (three letter code)

H-Ser-Phe-Ile-Glu-Asp-Leu-Leu-Phe-Asn-Lys-OH

Purity >95%
Storage -20°C
References

Rosen et al., (2022). SARS-CoV-2 spike antigen quantification by targeted mass spectrometry of a virus-based vaccine. J. Virol. Methods, 303: 114498. PMID: 35217103. 

Manufactured in: United Kingdom
Material Safety Data Sheet (MSDS)

SARS-CoV-2 Spike (S) protein is one of the four essential structural proteins from the coronavirus SARS-CoV-2. S protein is a large, class I viral transmembrane protein essential for viral entry into the cell via binding to the host angiotensin-converting enzyme 2 (ACE2) receptor. S assembles as a trimer on the surface of the virion, giving it its distinctive “corona” or crown-like appearance. The ectodomains of S proteins are divided into two subunits, S1 and S2. S1 helps in host receptor binding and is further divided into two subdomains: N-terminal domain (NTD) and C-terminal domain (CTD), both of which act as receptor-binding domains. The S1 CTD contains the receptor-binding motif (RBM). The S2 subunit accounts for fusion. The spike (816-825) peptide has been identified as an antigen and has the capacity for a broad range of applications. Spike (816-825) peptide is suitable for specific and rapid identification of SARS-CoV-2 by liquid chromatography with mass spectroscopy. Alternatively, it could be used as a vaccine quantification method to allow batch consistency. 

SARS-CoV-2 Spike (816-825)

Cat No.Pack SizePriceQty.
1mg£110.00
25nmol£85.00
£85.00
Bulk Quote