SARS-CoV-2 Spike (1197-1206)


  • Description

  • Application Data


LIDLQELGKY is an epitope from the SARS-CoV-2 spike protein (1197-1206). It can be an epitope for anti-viral targeting.

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Application Data

Catalogue number crb1001804
Molecular Weight 1190.7
Sequence (one letter code)


Sequence (three letter code)


Purity >95%
Storage -20°C

Ahmed et al., (2020). Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies. Viruses, 12(3): 254. DOI: 10.3390/v12030254.

Manufactured in: United Kingdom
Data Sheet Data Sheet Material Safety Data Sheet (MSDS)

The SARS-CoV-2 spike protein is present on the outside of the virus particles and can bind to angiotensin-converting enzyme II (ACE2) present on the host cells. The C-terminal receptor binding domain (RBD) of the spike protein binds to the N-terminal peptidase M2 domain of ACE2. This receptor binding results in the internalisation of the virus-receptor complex and is, therefore the mechanism of entry of SARS-CoV-2 into host cells.

The spike protein residues LIDLQELGKY (1197-1206) have been identified as a T-cell epitope with a predicted HLA restriction. Immune targeting of confirmed epitopes may potentially offer protection against SARS-CoV-2 and help the development of vaccines for long-lasting immunity.

SARS-CoV-2 Spike (1197-1206)

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