PTH (1-13) Human SVSEIQLMHNLGK-acid

  • Description

  • Application Data

Description

N-terminal tryptic peptide of parathyroid hormone (PTH), used for quantification and optimisation in LC-MS/MS

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Application Data

Catalogue number crb1000436
Molecular Weight 1454.8
Sequence (one letter code) SVSEIQLMHNLGK-acid
Sequence (three letter code) H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-OH
Purity >95%
Storage -20°C
References

Lee et al (2014) Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair. J. Orthop. Res. 33(1) 17 PMID: 25266795

Nikitovic et al (2016) Parathyroid hormone/parathyroid hormone-related peptide regulate osteosarcoma cell functions: Focus on the extracellular matrix (Review). Oncol. Rep. 36(4) 1787 PMID: 27499459

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

N-terminal tryptic peptide of parathyroid hormone (PTH), used for quantification and optimisation in LC-MS/MS assays.

PTH is an 84-amino-acid polypeptide hormone (PTH 1-84) which is secreted by the parathyroid glands along with its fragments (such as PTH 1-34 and PTH 7-84). PTH increases calcium and decrease phosphate levels in the blood and the abundance of PTH-derived peptides is regulated by blood calcium levels. PTH inhibits the bone growth-promoting activity of osteoblasts and induces osteoclasts to resorb bone and release calcium and phosphate ions into the blood. PTH binds to and activates the receptor parathyroid hormone receptor 1 (PTHR1). PTHR1 is a G-protein-coupled receptor (GPCR) which regulates mineral ion homeostasis, bone turnover and skeletal development

PTH (1-13) Human

Cat No.Pack SizePriceQty.
1mg£110.00
0.5mg£85.00
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