Nociceptin is an endogenous ligand for the NOP opioid receptor. Administration of nociceptin leads to sensations of pain and is associated with memory, learning, and anxiety.
Catalogue number crb1001714 Molecular Weight 1808.0 Sequence (one letter code)
Sequence (three letter code)
Purity >95% References
Li et al., (2022). Rostromedial tegmental nucleus nociceptin/orphanin FQ (N/OFQ) signaling regulates anxiety- and depression-like behaviors in alcohol withdrawn rats. Neuropsychopharmacol. doi: 10.1038/s41386-022-01482-3.
Manufactured in: United Kingdom
Nociceptin is a potent anti-analgesic, effectively counteracting the effect of pain-relievers. A neuropeptide that modulates nociception, it acts by binding the nociceptin receptor (NOP). Nociceptin does not bind to μ, δ, or κ opioid receptors and thus lacks the addictive potential. Administration of nociceptin leads to sensations of pain and is associated with memory, learning, eating, and anxiety.