• Description

  • Application Data


Anti-microbial peptide with activity against several human cancer cell lines. Most potent against CCRF-CEM T lymphoblastoid cells.

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Application Data

Catalogue number crb1000038
Molecular Weight 2007.53
Sequence (one letter code) GTGLPMSERRKIMLMMR-acid
Sequence (three letter code)


Purity >95%
Storage - 20 ° C

Slaninová et al (2012) Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides 33(1) 18 PMID: 22100226

Tonk et al (2016) Insect antimicrobial peptides: potential tools for the prevention of skin cancer. Appl. Microbiol. Biotechnol. 100(17) 7397 PMID: 27418360

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

Thisanti-microbial peptide (AMP) has been shown to cause lysis of several human cancer cell lines. Macropin-2 is most potent against CCRF-CEM T lymphoblastoid (human acute lymphoblastic leukemia) cells. At higher concentrations Macropin-2 also causes lysis of human umbilical vein endothelial cells (HUVEC), rat intestinal epithelial cells (IEC), human cervix carcinoma (HeLa) cells and human colon adenocarcinoma (SW480).

Macropin 2

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