Glucagon like-peptide-2 (GLP-2)

DGSFSDEMNTILDNLAARDFINWLIQTKITD-acid

  • Description

  • Application Data

Description

Glucagon like-peptide-2 (GLP-2) is a gut hormone produced in the enteroendocrine L cells of gastrointestinal tract by the cleavage of the 160-amino-acid proglucagon molecule.

See full description

Application Data

Catalogue number crb1001638
Molecular Weight 3555.7
Sequence (one letter code)

DGSFSDEMNTILDNLAARDFINWLIQTKITD-acid

Sequence (three letter code)

H-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH

Purity >95%
Storage -20°C
References

Jeppesen (2012) Teduglutide, a novel glucagon-like peptide 2 analog, in the treatment of patients with short bowel syndrome. Ther. Adv. Gastroenterol. 5(3) 159 PMID: 22570676

Schwartz et al (2016) Long-Term Teduglutide for the Treatment of Patients With Intestinal Failure Associated With Short Bowel Syndrome. Clin.Transl. Gastroenterol. 7(2) e142 PMID: 26844839

Manufactured in: United Kingdom
Material Safety Data Sheet (MSDS)

Glucagon like-peptide-2 (GLP-2) is a gut hormone produced in the enteroendocrine L cells of gastrointestinal tract by the cleavage of the 160-amino-acid proglucagon molecule. GLP-2 is secreted following the ingestion of food and carries out its activities via the GLP-2 G-protein coupled receptors (GLP-2Rs). GLP-2 has a range of roles within the cell, including: anti-inflammatory effects; promoting the expansion of the intestinal mucosa; stimulating intestinal blood flow; inhibiting gastric acid secretion and gastric emptying; increasing intestinal barrier function and enhancing nutrient and fluid absorption.

Glucagon like-peptide-2 (GLP-2)

Cat No.Pack SizePriceQty.
0.5mg£190.00
1mg£260.00
Bulk Quote

Download Family PDF

You may also like…