Fz7-21 Ac-LPSDDLEFWCHVMY-amide
Description
Application Data
Description
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Binds to the cysteine rich domain of the Frizzled 7 receptor and inhibits Wnt signalling in cultured cells and stem cell function in intestinal organoids.
Application Data
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Catalogue number crb1001175 Molecular Weight 1794.8 Sequence (one letter code) Ac-LPSDDLEFWCHVMY-amide Sequence (three letter code) Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2
Purity >95% Storage -20°C References Nile et al (2018) A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat. Chem. Biol. 14 582 PMID: 29632413
Manufactured in: United Kingdom Binds to the cysteine rich domain of the Frizzled 7 receptor and inhibits Wnt signalling in cultured cells and stem cell function in intestinal organoids.