Duck liver-derived peptide 3
APGIIPR-acid
Description
Application Data
Description
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Duck liver-derived peptide 3 is a novel bioactive peptide with high antioxidant activity.
Application Data
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Data Sheet Data Sheet Material Safety Data Sheet (MSDS)Catalogue number crb1001743 Molecular Weight 722.5 Sequence (one letter code) APGIIPR-acid
Sequence (three letter code) H-Ala-Pro-Gly-Ile-Ile-Pro-Arg-OH
Purity >95% Citations Fan et al., (2023). Preparation and characterization of duck liver-derived antioxidant peptides based on LC-MS/MS, molecular docking, and machine learning. LWT, 175: 114479. doi: 10.1016/j.lwt.2023.114479.
References Lee et al., (2010). Purification and characterisation of an antioxidative peptide from enzymatic hydrolysates of duck processing by-products. Food Chem, 123(2): 216. doi: 10.1016/j.lwt.2023.114479.
Manufactured in: United Kingdom Duck liver-derived peptide 3 is a novel bioactive peptide with high antioxidant activity. The antioxidant activity is attributed to forming hydrogen bonds between their amino acid residues and free radical molecules. Duck liver-derived peptide 2 increases the activities and mRNA expression levels of intracellular antioxidant enzymes (SOD, CAT, and GSH-Px) in HepG2 oxidative damage cell models. Duck liver-derived peptide 3 can reduce the content of malondialdehyde (MDA) and reactive oxygen species (ROS) accumulation, thereby inhibiting intracellular oxidative damage. Duck liver-derived peptide 3 has the following activity: immunomodulation, ACE inhibitor, dipeptidyl peptidase IV inhibitor, and antioxidant. This peptide may be used in the research for food-derived bioactive peptides for modified-food development.
Of the identified duck-liver derived peptides, this is the only peptide in this group that has a proposed site of action as a HLA class I histocompatibility antigen.
