Cytokeratin 9 (47-59) Heavy

FSSSSGYGGGSS-[U-13C6,15N4-Arg]-acid

  • Description

  • Application Data

Description

Cytokeratin 9 (47-59) is derived from the cytoskeleton component cytokeratin, a family of intermediate filamentous proteins which have structural and mechanical functions in the cell. The arginine residue at position 13 is isotopically labelled.

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Application Data

Catalogue number crb1300962
Molecular Weight 1244.5
Sequence (one letter code)

FSSSSGYGGGSS-[U-13C6,15N4-Arg]-acid

Sequence (three letter code)

H-Phe-Ser-Ser-Ser-Ser-Gly-Tyr-Gly-Gly-Gly-Ser-Ser-[U-13C6,15N4-Arg]-OH

Purity >95%
Storage -20°C
References

Olivieri et al (2018) Phenotypic characterization of the SIRC (Statens Seruminstitut Rabbit Cornea) cell line reveals a mixed epithelial and fibroblastic nature. Exp. Eye Res. 172 123 doi: https://doi.org/10.1016/j.exer.2018.04.004

Osman and Kora (2006) Immunohistochemical Detection of Cytokeratin 14 in Developing Enamel Organ of Rat Molars. Egyptian Dental J. 52 1399

Manufactured in: United Kingdom
Material Safety Data Sheet (MSDS)

Cytokeratin 9 (47-59) is derived from the cytoskeleton component cytokeratin, a family of intermediate filamentous proteins which have structural and mechanical functions in the cell. The cytokeratin family contains cytokeratins 1-20, where cytokeratins 1-8 are categorised as being type II basic, while cytokeratins 9-20 are categorised as being type I acidic. Cytokeratins 1 to 20 have been ordered regarding their molecular weight, where cytokeratin 1 has the highest molecular weight and cytokeratin 20 has the smallest.

The expression of Cytokeratins in the epithelial tissues is dependent on where it is located in the body and at which stage of differentiation and development the organism is at. Consequently cytokeratins can be used as tissue specific markers (for example an ocular surface epithelia marker) and to investigate cell differentiation progression.

The arginine residue at position 13 is isotopically labelled with carbond-13 (6) and nitrogen-15 (4).

Cytokeratin 9 (47-59) Heavy

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£260.00
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