Cyclo-CLLFVY Cyclo[CLLFVY]

  • Description

  • Application Data

Description

Cyclo-CLLFVY is a cyclic peptide which binds to the PAS-B domain of HIF-1α, thus inhibiting HIF-1 dimerisation and HIF-1 mediated hypoxia signalling.

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Application Data

Catalogue number crb1001365
Molecular Weight 738.4
Sequence (one letter code) Cyclo[CLLFVY]
Sequence (three letter code)

Cyclo-[Cys-Leu-Leu-Phe-Val-Tyr]

Purity >95%
Storage -20°C
References

Miranda et al (2013) A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells. J. Am. Chem. Soc. 135(28) 10418 PMID: 23796364

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

Cyclo-CLLFVY is a cyclic peptide which binds to the PAS-B domain of HIF-1α, thus inhibiting HIF-1 dimerisation and HIF-1 mediated hypoxia signalling.

Cyclo-CLLFVY

Cat No.Pack SizePriceQty.
0.5mg£170.00
1mg£220.00
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