CSK substrate KKKKEEIYFFF-amide

  • Description

  • Application Data

Description

Substrate peptide for C-terminal Src kinase (Csk) for use in kinase assays

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Application Data

Catalogue number crb1000320
Molecular Weight 1504.8
Sequence (one letter code) KKKKEEIYFFF-amide
Sequence (three letter code) H-Lys-Lys-Lys-Lys-Glu-Glu-Ile-Tyr-Phe-Phe-Phe-NH2
Molecular Weight 1504.8
Purity >95%
References

Samarasekera and Auld (2018) C-terminal Src kinase (Csk) regulates the tricellular junction protein Gliotactin independent of Src. Mol. Biol. Cell 29(2) 123 PMID: 29167383

 

Lee et al (2016) Gene Silencing and Haploinsufficiency of Csk Increase Blood Pressure. PLoS ONE 11(1) e0146841 PMID: 26751575

Data Sheet Material Safety Data Sheet (MSDS)

Substrate peptide for C-terminal Src kinase (Csk) for use in kinase assays. Csk is a cytosolic tyrosine kinase that is closely related to the kinase Src and is a well-known negative regulator of Src family kinases. Csk has both tumour suppressor and oncogenic properties and has also been implicated in regulating blood pressure, making Csk a novel therapeutic target for hypertension disorders.

CSK substrate

Cat No.Pack SizePriceQty.
1mg£110.00
0.5mg£85.00
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