CSK substrate KKKKEEIYFFF-amide
Description
Application Data
Description
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Substrate peptide for C-terminal Src kinase (Csk) for use in kinase assays
Application Data
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Catalogue number crb1000320 Molecular Weight 1504.8 Sequence (one letter code) KKKKEEIYFFF-amide Sequence (three letter code) H-Lys-Lys-Lys-Lys-Glu-Glu-Ile-Tyr-Phe-Phe-Phe-NH2 Molecular Weight 1504.8 Purity >95% References Samarasekera and Auld (2018) C-terminal Src kinase (Csk) regulates the tricellular junction protein Gliotactin independent of Src. Mol. Biol. Cell 29(2) 123 PMID: 29167383
Lee et al (2016) Gene Silencing and Haploinsufficiency of Csk Increase Blood Pressure. PLoS ONE 11(1) e0146841 PMID: 26751575
Substrate peptide for C-terminal Src kinase (Csk) for use in kinase assays. Csk is a cytosolic tyrosine kinase that is closely related to the kinase Src and is a well-known negative regulator of Src family kinases. Csk has both tumour suppressor and oncogenic properties and has also been implicated in regulating blood pressure, making Csk a novel therapeutic target for hypertension disorders.