Click Maier8

4-Pentynyl-GKKALKLAAKLLKK-amide

  • Description

  • Application Data

Description

Maier8 is a cell-penetrating peptide (CPP) labelled at the N-terminus with an alkyne attachment for ease of reaction with an opposite Click reactive partner (azide).

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Application Data

Catalogue number crb1000130
Molecular Weight 1588.1
Sequence (one letter code)

4-Pentynyl-GKKALKLAAKLLKK-amide

Sequence (three letter code)

4-Pentynyl-Gly-Lys-Lys-Ala-Leu-Lys-Leu-Ala-Ala-Lys-Leu-Leu-Lys-Lys-NH2

Purity >95%
Storage -20°C
References

Li et al., (2013). Click chemistry in peptide-based drug design. Molecules, 18(8): 9797. doi: 10.3390/molecules18089797.

Maier et al., (2006). Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids. J. Med. Chem., 49(8): 2534. doi: 10.1021/jm051275y.

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

Maier8 is a short basic amphipathic peptide that functions as a cell-penetrating peptide (CPP). Maier8 has been studied in comparison to other CPPs and found to be highly efficient at crossing into the cell without causing cytotoxicity. Furthermore, Maier8 has a long half-life which is vital for effective delivery of the conjugate.

Maier8 is labelled at the N-terminus with an alkyne attachment for ease of reaction with an opposite Click reactive partner (azide). Azide-alkyne cycloaddition has become the most popular Click reaction. Alkyne-Maier8 allows a wide variety of applications, particularly for conjugation, modification, and drug delivery.

Click Maier8

Cat No.Pack SizePriceQty.
0.5mg£85.00
1mg£110.00
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