• Description

  • Application Data


Potent antimicrobial peptide against a broad spectrum of microorganisms

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Application Data

Catalogue number crb1000166
Molecular Weight 2434.85
Sequence (one letter code) TRSSRAGLQFPVGRVHRLLRK-acid
Sequence (three letter code) H-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-OH
Molecular Weight 2434.85
Purity >95%

Park et al (2000) Structure-activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: The proline hinge is responsible for the cell-penetrating ability of buforin II. PNAS 97(15) 8245 PMID: 10890923

Material Safety Data Sheet (MSDS)

Buforin II is a highly potent antimicrobial peptide which was derived from buforin I, a peptide isolated from the stomach of the Asian toad, Bufo bufo garagrizans. Buforin II is an α-helical antimicrobial peptide, however it has far stronger antimicrobial activity against a broad spectrum of microorganisms compared with other α-helical antimicrobial peptides. Buforin II may have a different mode of action to that of other α-helical peptides targeting nucleic acids instead of cell membranes.

Buforin II

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