Beclin-1 TNVFNATFHIWHSGQFGT-acid

  • Description

  • Application Data

Description

The Beclin-1 peptide is derived from a region of the Beclin-1 protein, which interacts with a newly identified negative regulator of autophagy, GAPR-1 (also called GLIPR2) to act as a potent inducer of autophagy.

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Application Data

Catalogue number crb1000187
Molecular Weight 2064.22
Sequence (one letter code) TNVFNATFHIWHSGQFGT-acid
Sequence (three letter code)

H-Thr-Asn-Val-Phe-Asn-Ala-Thr-Phe-His-Ile-Trp-His-Ser-Gly-Gln-Phe-Gly-Thr-OH

Purity >95%
References

Shoji-Kawata et al (2013) Identification of a candidate therapeutic autophagy-inducing peptide Nature 494 201 https://www.ncbi.nlm.nih.gov/pubmed/23364696

Kang et al (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell death and differentiation 18(4) 571 PMID: 21311563.

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

The Beclin-1 peptide is derived from a region of the Beclin-1 protein, which interacts with a newly identified negative regulator of autophagy, GAPR-1 (also called GLIPR2) to act as a potent inducer of autophagy. Autophagy is an essential process that maintains cellular homeostasis and carries out lysosome-mediated degradation of unwanted proteins in the cytoplasm. It is often examined when looking at disease pathways because of this regulatory function. While the immune system initiates the removal of viruses and pathogens through the autophagic pathway, some viruses (such as HIV) are able to evade this process. 

Beclin-1

Cat No.Pack SizePriceQty.
1mg£110.00
0.5mg£85.00
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