Anti-citrullinated α-Enolase antibody 20ug
Description
Application Data
Description
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α-Enolase is a multifunctional enzyme; it is a neutrophin, a heat-shock protein, and a glycolytic catalyst. α-Enolase is also an autoantigen and stimulates immunoglobulin production. The production of antibodies against the citrullinated form of α-enolase (whereby positive Arg residues are converted into citrulline) is a hallmark of rheumatoid arthritis. α-Enolase also functions in the fibrolytic… Read more »
Application Data
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Catalogue number | crb2005010d |
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α-Enolase is a multifunctional enzyme; it is a neutrophin, a heat-shock protein, and a glycolytic catalyst. α-Enolase is also an autoantigen and stimulates immunoglobulin production. The production of antibodies against the citrullinated form of α-enolase (whereby positive Arg residues are converted into citrulline) is a hallmark of rheumatoid arthritis. α-Enolase also functions in the fibrolytic system, as a plasminogen receptor, and binds Myc to repress c-myc.