ACTH (18-39) Human 1mg RPVKVYPNGAEDESAEAFPLEF-acid

£110.00
  • Description

  • Application Data

Description

Segment 18-39 of adrenocorticotropic hormone (ACTH). ACTH, also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically… Read more »

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Application Data

Catalogue number crb1000077j
Molecular Weight 2465.67
Sequence (one letter code) RPVKVYPNGAEDESAEAFPLEF-acid
Sequence (three letter code)

H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH

Purity >95%
Storage - 20 ° C
References

Stewart, PM. et al. Clin Endocrinol 40, 199 (1994)
Elias, LL. and AJ. Clark, Braz J Med Biol Res 33, 1245 (2000)
Latronico, AC. Braz J Med Biol Res 33, 1249 (2000)

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

Segment 18-39 of adrenocorticotropic hormone (ACTH). ACTH, also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex

ACTH (18-39) Human 1mg

1mg
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