ACTH (1-39) Human 1mg SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF-acid

£220.00
  • Description

  • Application Data

Description

Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a cleavage product from the larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal… Read more »

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Application Data

Catalogue number crb1000076j
Molecular Weight 4541.07
Sequence (one letter code) SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF-acid
Sequence (three letter code) H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
Molecular Weight 4541.07
Purity >95%
Storage - 20 ° C
References Stewart, PM. et al. Clin Endocrinol 40, 199 (1994) Elias, LL. and AJ. Clark, Braz J Med Biol Res 33, 1245 (2000) Latronico, AC. Braz J Med Biol Res 33, 1249 (2000)
Data Sheet Material Safety Data Sheet (MSDS)

Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a cleavage product from the larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex

ACTH (1-39) Human 1mg

1mg
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