Acetyl-Adhesin Ac-QLKTADLPAGRDETTSFVLV-amide

  • Description

  • Application Data

Description

An antimicrobial peptide (AMP) which can inhibit in vitro binding of a cell surface adhesin of Streptococcus mutans to salivary receptors.

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Application Data

Catalogue number crb1000026
Molecular Weight 2202.46
Sequence (one letter code) Ac-QLKTADLPAGRDETTSFVLV-amide
Sequence (three letter code)

Ac-Gln-Leu-Lys-Thr-Ala-Asp-Leu-Pro-Ala-Gly-Arg-Asp-Glu-Thr-Thr-Ser-Phe-Val-Leu-Val-NH2

Purity >95%
Storage - 20 ° C
References

Hassan et al., (2012). Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance. J. Appl. Microbiol. 113(4): 723. https://doi.org/10.1111/j.1365-2672.2012.05338.

 

Kelly et al., (1999). A synthetic peptide adhesion epitope as a novel antimicrobial agent. Nat. Biotechnol. 55: 42. https://doi.org/10.1038/5213.

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

Bacterial cell invasion begins by initially adhering to mucosa of the oro-intestinal, nasorespiratory, or genitourinary tract by specific adhesins. This leads to colonization of the region and ultimately infection. Studies showed acetyl-adhesin can inhibit binding of S. mutans to salivary receptors and can prevent S. mutans colonising the teeth. This suggests the peptide may be a useful antimicrobial agent against bacterial mucosal colonisation, particularly tooth decay.

Acetyl-Adhesin

Cat No.Pack SizePriceQty.
1mg£110.00
0.5mg£85.00
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