Novel cell penetrating peptide derived from the tumour suppressor protein p14ARF. Contains N-terminal 5-carboxyfluorescein (5-FAM) tag
Catalogue number crb1100287 Molecular Weight 3009.61 Sequence (one letter code) [5-FAM]-MVTVLFRRLRIRRACGPPRVRV-amide Sequence (three letter code) [5-FAM]-Met-Val-Thr-Val-Leu-Phe-Arg-Arg-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-Arg-Val-NH2 Molecular Weight 3009.61 Purity >95% References
Rostami et al., (2018). M918: A Novel Cell Penetrating Peptide for Effective Delivery of HIV-1 Nef and Hsp20-Nef Proteins into Eukaryotic Cell Lines. Curr HIV Res. 16(4): 280. PMID: 30520377
Novel cell-penetrating peptide (CPP). M918 was derived from the tumour suppressor protein p14ARF and can be utilized for both covalent and non-covalent delivery of macromolecules in animal and plant cells. CPPs are able to cross the cell membrane at low micromolar concentrations without causing significant membrane damage in vivo and in vitro.
This cationic CPP Peptide is labelled with an N-terminal 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.