KSHV ORF65 peptide
Description
Application Data
Description
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Peptide from open reading frame 65 (ORF65) of Kaposi’s sarcoma-associated herpesvirus (KSHV)
Application Data
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Data Sheet Material Safety Data Sheet (MSDS)Catalogue number crb1200467 Antibody KSHV ORF65 peptide Antigen Peptide KSHV ORF65 peptide Protein ID GenBank: ABD28922.1. UniProtKB - Q2HR63 Aliases Kaposi sarcoma-associated herpesvirus (KSHV) ORF65, Human gammaherpesvirus 8 ORF65, HHV-8 ORF65, Small capsomere-interacting protein Cross-Reactivity KSHV Target Protein Species KSHV Storage Stabilisers -20°C Specificity Protein Storage -20°C References Lin, S., Sun, R., Heston, L., Gradoville, L., Shedd, D., Haglund, K., Rigsby, M., Miller, G. (1997). Identification, expression, and immunogenicity of Kaposi’s sarcoma-associated herpesvirus-encoded small viral capsid antigen. J Virol, 71(4), 3069-76. PMID: 9060668
Antigenic peptide corresponding to region of lytic-phase viral capsid antigen (vp19)/small viral capsid antigen (sVCA), encoded by open reading frame 65 (ORF65) from Kaposi’s sarcoma-associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8). HHV8/KSHV belongs to the gamma-2 or rhadinovirus sub-lineage of the Gammaherpesvirinae subfamily and is strongly associated with AIDS related malignancies. These malignancies include; Kaposi’s sarcoma (KS) – a rare cancer that causes skin and mouth lesions; primary effusion lymphoma (PEL) – a B-cell lymphoma; and Castleman’s disease – characterised by over proliferation of the lymph node.