DBCO-PEG5-NHS Ester is an amine-reactive labelling reagent with enhanced stability and solubility in water.
Catalogue number crb7108344 Molecular Weight 693.74 Chemical Composition C36H43N3O11 Appearance Viscous oil or amorphous solid Solubility DMF, DMSO, DCM, THF, Chloroform Chemistry NHS Ester Purity >95% (HPLC) cas 1378531-80-6 Storage -20C Manufacturer Product Number A102P
DBCO-PEG5-NHS Ester is an amine-reactive building block which reacts specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The polyethylene glycol (PEG) spacer arm is hydrophilic and imparts water solubility which is transferred to the labelled molecule, therefore, reducing aggregation of labelled proteins in the solution. It also provides a long, flexible connection that minimises steric hindrance in reactions with complementary azide-containing molecules.