• Description

  • Application Data


DBCO-PEG5-Acid is a non-activated, amine-reactive building block with a PEG5 spacer arm (enhancing its solubility in aqueous media).

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Application Data

Catalogue number crb7108351
Molecular Weight 596.67
Chemical Composition C32N40N2O9
Appearance Yellow to slightly orange oil
Solubility DMF, DMSO, DCM, THF, Chloroform
Chemistry Acid
Purity >95% (HPLC)
cas N/A
Storage -20C
Manufacturer Product Number A101P
Material Safety Data Sheet (MSDS)

DBCO-PEG5-Acid is an amine-reactive non-activated building block used for forming a stable amide bond when reacted with an amine-containing molecule in the presence of activators (e.g. EDC, HATU). It also has an enhanced solubility in aqueous media due to the PEG5 spacer arm. DBCO reagents are the most commonly used substrates for strain-promoted copper-free Click chemistry reactions with azide-containing compounds or biomolecules, forming stable triazole linkages.


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