• Description

  • Application Data


DBCO-C6-Acid is a non-activated building block with improved solubility and functionalization efficiency.

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Application Data

Catalogue number crb7108350
Molecular Weight 333.83
Appearance Slightly grey to slightly orange solid
Solubility DMSO, DMF, DCM, THF, Chloroform
Chemistry Acid
Purity >95% (HPLC)
cas 1425485-72-8
Storage -20C
Manufacturer Product Number A101
Material Safety Data Sheet (MSDS)

DBCO-C6-Acid (or ADIBO/DIBAC) is a non-activated building block commonly used for synthesis of complex molecules for copper-free Click Chemistry reactions. Primary or secondary amines can react with DBCO groups in the presence of activators (e.g. EDC, HATU), forming a stable amide bond. The extended 6-carbon long spacer arm makes this reagent more soluble in commonly used organic solvents (e.g. dichloromethane, chloroform, THF, ethyl acetate) and also greatly improves coupling efficiency and stability of conjugates.


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