Anti-Phospho-GluR2 (pS880) antibody 50ug
Description
Application Data
Description
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Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and is involved in synaptic transmission. Binding of L-glutamate to the receptor induces a conformation change which leads to Ion channel opening before rapidly desensitising.
Application Data
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Material Safety Data Sheet (MSDS)Catalogue number crb2005005e Antibody Anti-Phospho-GluR2 (pS880) antibody 50ug Antigen Peptide KLH conjugated synthetic peptide crb1200275e Protein ID UniProtKB - Q14416 Aliases GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, glutamate ionotropic receptor AMPA type subunit 2 Cross-Reactivity Rat Target Protein Species Rat Host Species Anti-Rabbit Antibody Type Polyclonal Label Unconjugated Concentration 1mg/ml Validation WB/ELISA Target phosphorylated GluR2 (pS880) Storage Stabilisers This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles. Family Glutamate-gated ion channel family. Disease Area Neurodegenerative diseases Specificity PTM - Phosphorylated serine 880 Post-translational Modification Phosphorylation of Serine 880 Storage This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles. Citations Liu et al., (2010). Journal of Alzheimer’s Disease. 21 (2): 655-66. Lin et al. (2007). J Neurosci. 27(50):13903-8. Huganir, et al. (2001).Neuropharmacology. 41: 672-679. References Liu et al., (2010). Journal of Alzheimer’s Disease. 21 (2): 655-66.
Lin et al. (2007). J Neurosci. 27(50):13903-8.
Huganir, et al. (2001).Neuropharmacology. 41: 672-679.Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and is involved in synaptic transmission. Binding of L-glutamate to the receptor induces a conformation change which leads to Ion channel opening before rapidly desensitising.