Anti-Phospho-GluR2 (pS880) antibody 50ug

£220.00
  • Description

  • Application Data

Description

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and is involved in synaptic transmission. Binding of L-glutamate to the receptor induces a conformation change which leads to Ion channel opening before rapidly desensitising.

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Application Data

Catalogue number crb2005005e
Antibody Anti-Phospho-GluR2 (pS880) antibody 50ug
Antigen Peptide KLH conjugated synthetic peptide crb1200275e
Protein ID UniProtKB - Q14416
Aliases GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, glutamate ionotropic receptor AMPA type subunit 2
Cross-Reactivity Rat
Target Protein Species Rat
Host Species Anti-Rabbit
Antibody Type Polyclonal
Label Unconjugated
Concentration 1mg/ml
Validation WB/ELISA
Target phosphorylated GluR2 (pS880)
Storage Stabilisers This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles.
Family Glutamate-gated ion channel family.
Disease Area Neurodegenerative diseases
Specificity PTM - Phosphorylated serine 880
Post-translational Modification Phosphorylation of Serine 880
Storage This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles.
Citations Liu et al., (2010). Journal of Alzheimer’s Disease. 21 (2): 655-66. Lin et al. (2007). J Neurosci. 27(50):13903-8. Huganir, et al. (2001).Neuropharmacology. 41: 672-679.
References

Liu et al., (2010). Journal of Alzheimer’s Disease. 21 (2): 655-66.
Lin et al. (2007). J Neurosci. 27(50):13903-8.
Huganir, et al. (2001).Neuropharmacology. 41: 672-679.

Material Safety Data Sheet (MSDS)

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and is involved in synaptic transmission. Binding of L-glutamate to the receptor induces a conformation change which leads to Ion channel opening before rapidly desensitising.

Anti-Phospho-GluR2 (pS880) antibody 50ug

50ug
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