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Photomicrographs demonstrating positive cytoplasmic staining for 2SC in a fumarate hydratase deficient (HLRCC related) renal carcinoma. Antigen Retrieval on FFPE tissue: heat-induced epitope retrieval (HIER) for 30 min at 97 °C in the manufacturerʼs alkaline retrieval solution ER2 (VBS part no: AR9640) on the Leica BondMax Autostainer. Anti-2SC antibody 6773 

IHC image provided courtesy of Prof. Anthony Gill